{"id":38258,"date":"2021-04-26T18:32:42","date_gmt":"2021-04-26T18:32:42","guid":{"rendered":"https:\/\/www.xatakaciencia.com\/genetica\/no-te-gusta-arroz-dorado-para-producir-vitamina-a-quiza-prefieras-levaduras-transgenicas-que-se-instalen-tus-intestinos"},"modified":"2021-04-26T18:32:42","modified_gmt":"2021-04-26T18:32:42","slug":"si-no-te-gusta-el-arroz-dorado-para-producir-vitamina-a-quiza-prefieras-levaduras-transgenicas-que-se-instalen-en-tus-intestinos","status":"publish","type":"post","link":"http:\/\/forocilac.org\/en\/si-no-te-gusta-el-arroz-dorado-para-producir-vitamina-a-quiza-prefieras-levaduras-transgenicas-que-se-instalen-en-tus-intestinos\/","title":{"rendered":"If you don't like golden rice to produce vitamin A, you may prefer transgenic yeast that settles in your intestines"},"content":{"rendered":"

\n \"Si\n <\/p>\n

Traditionally, the golden rice<\/a>, because it is a genetically modified organism, has entailed fierce activist resistance from a certain ideological spectrum<\/strong>. <\/p>\n

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You will have to ask them what do you think about this<\/a>: yeast pills designed with genetic engineering that settle in your intestine and They synthesize vitamin A from what you eat<\/strong> (something that could happen soon given the results obtained in mouse models).<\/p>\n

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Transgenic yeasts in mice<\/h2>\n

Most yeast species cannot survive in the intestine of mammals<\/strong>: Heat and acidity are beyond your tolerance limits. But Saccharomyces boulardii<\/em> It not only grows easily in the intestine of mammals, but also inhibits pathogenic intestinal infections in the mammalian host.<\/p>\n

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\n \"En Canadá ya puede adquirirse salmón transgénico\"
\n <\/a>\n <\/div>\n
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\n In Xataka Science<\/a>\n <\/div>\n

Transgenic salmon can now be purchased in Canada<\/a>\n <\/div><\/div><\/div>\n<\/div>\n

Like golden rice, it is a transgenic variety that can fill vitamin A deficiencies, maybe one day this yeast can do it more effectively<\/strong>.<\/p>\n

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In a new step for synthetic biology, a group of researchers has opened new biosynthetic pathways<\/a> in S. boulardii that allow the production of vitamin precursors (such as beta-carotene, a precursor of vitamin A) and drugs (such as violacein, a natural drug with anti-inflammatory properties) in the intestine of mice. They thus demonstrated CRISPR-mediated genome editing with high efficiency (95%) in this yeast strain.<\/strong>.<\/p>\n

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\n \"Sopas Campbell se enorgullece de etiquetar sus productos como transgénicos\"
\n <\/a>\n <\/div>\n
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\n In Xataka Science<\/a>\n <\/div>\n

Campbell's Soups are proud to label their products as GMO<\/a>\n <\/div><\/div><\/div>\n<\/div>\n

The researchers reported that S. boulardii formed stable colonies in germ-free mice for more than 30 days, competing for space with other gut-resident microbes.<\/p>\n

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The researchers then tested the modified S. boulardii in the mouse model and found that the yeast cells successfully synthesized beta-carotene in the intestine of mice<\/strong>. By comparing the total mass of additional beta-carotene recovered in feces to the beta-carotene present in the initial dose of probiotics, the authors estimated that the germ-free mice produced 194 micrograms of beta-carotene in approximately 14 days.<\/p>\n

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\n \"Este arroz transgénico no solo combatirá el hambre sino el cambio climático\"
\n <\/a>\n <\/div>\n
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\n In Xataka Science<\/a>\n <\/div>\n

This genetically modified rice will not only combat hunger but also climate change<\/a>\n <\/div><\/div><\/div>\n<\/div>\n

This proof-of-concept study inspires further questions about the amount of beta-carotene absorbed by the mice, the biological relevance of the amounts produced, and, most importantly, If the process can be replicated in humans<\/strong>. Be that as it may, I'm sure Greenpeace is against it.<\/a>.<\/p>\n