{"id":74920,"date":"2023-09-14T18:00:00","date_gmt":"2023-09-14T18:00:00","guid":{"rendered":"https:\/\/elpais.com\/ciencia\/2023-09-14\/un-raton-con-100000-neuronas-humanas-en-su-cerebro-ilumina-el-enigma-del-alzheimer.html"},"modified":"2023-09-14T18:00:00","modified_gmt":"2023-09-14T18:00:00","slug":"un-raton-con-100-000-neuronas-humanas-en-su-cerebro-ilumina-el-enigma-del-alzheimer","status":"publish","type":"post","link":"https:\/\/forocilac.org\/en\/un-raton-con-100-000-neuronas-humanas-en-su-cerebro-ilumina-el-enigma-del-alzheimer\/","title":{"rendered":"A mouse with 100,000 human neurons in its brain illuminates the enigma of Alzheimer&#039;s"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/cloudfront-eu-central-1.images.arcpublishing.com\/prisa\/4MDXKWCP4NEIFFO47FOBELO4XQ.jpg\" width=\"1392\" height=\"629\" alt=\"Neuronas de rat\u00f3n (izquierda) y neuronas humanas degeneradas en el cerebro del rat\u00f3n con s\u00edntomas de alzh\u00e9imer.\"><\/img><\/p>\n<p>When a person ages and begins to lose their memory, to even forget the names of their loved ones, it is already too late. Alzheimer&#039;s has been silently destroying his brain for years. If its skull could be opened, dead neurons and accumulations of two characteristic proteins would be observed: amyloid and tau. The disease threatens to devastate civilization in the coming decades\u2014every year there are <a href=\"https:\/\/www.who.int\/es\/news-room\/fact-sheets\/detail\/dementia\">10 million new cases<\/a> of dementia\u2014but the scientific community still has no idea what causes it. An international team, in which the Spanish neuroscientist participates <a href=\"https:\/\/www.achucarro.org\/es\/personas\/amaia-arranz-mendiguren\/\">Amaia Arranz<\/a>, has introduced 100,000 human neurons into the brains of mice to try to investigate in vivo what happens during Alzheimer&#039;s. The authors have observed how cells perish and have managed to avoid this neuronal death with a simple oral treatment. Its preview is published this Thursday <a href=\"https:\/\/doi.org\/10.1126\/science.abp9556\">in the magazine <i>Science<\/i><\/a>, one of the temples of world science.<\/p>\n<p><a href=\"https:\/\/elpais.com\/ciencia\/2023-09-14\/un-raton-con-100000-neuronas-humanas-en-su-cerebro-ilumina-el-enigma-del-alzheimer.html\" >Keep reading<\/a><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/cloudfront-eu-central-1.images.arcpublishing.com\/prisa\/7M4DWD4RDBFT5DPTCQWRA47AQA.jpg\" width=\"800\" height=\"640\" alt=\"La investigadora Amaia Arranz, del Centro Vasco para la Neurociencia Ach\u00facarro.\"><\/img><\/p>","protected":false},"excerpt":{"rendered":"<p>A team of scientists manages to avoid neuronal death with oral drugs in rodents genetically modified to imitate dementia<\/p>","protected":false},"author":25,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[123],"tags":[],"class_list":{"0":"post-74920","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-portal"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/posts\/74920","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/comments?post=74920"}],"version-history":[{"count":2,"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/posts\/74920\/revisions"}],"predecessor-version":[{"id":74973,"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/posts\/74920\/revisions\/74973"}],"wp:attachment":[{"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/media?parent=74920"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/categories?post=74920"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forocilac.org\/en\/wp-json\/wp\/v2\/tags?post=74920"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}