Sleepless nights take their toll on the brain. More than it seems. Apart from tiredness or lack of concentration the following day, cognitive performance can suffer in the long term and more seriously. A study of the Pasqual Maragall Foundation, specialized in Alzheimer's research, has found modifications in brain structure that suggest a link between insomnia and the development of this neurodegenerative disease. Research, carried out with healthy people, has found that those who suffer from insomnia have changes in some areas of the brain that are also affected in the early stages of Alzheimer's. Brain damage in This neurological condition starts long before the patient develops the first symptoms.