Half the planet has passed, is passing or will pass through menopause. Around age 50, ovarian activity ceases in most women, menstruation disappears, reproductive hormones are no longer produced, and irreversible loss of fertility occurs. But, despite its impact on the life cycle of any woman, menopause It is still surrounded by scientific unknowns and stigma and silence on the street. A scientific review published in Magazine cell has reviewed the available evidence on the biology and consequences of menopause and has found gaps in knowledge in why it occurs, how it manifests and what is the best therapeutic approach to the symptoms, such as hot flushes, vaginal dryness or changes in mood. Although it is not a tortuous path for everyone, this vital process can be disabling for many, the authors point out. And they warn that more than 85% of women with menopausal symptoms do not receive effective treatment approved by regulatory agencies to treat them.