Electronic cigarettes cause inflammation in the intestine

By 08/01/2021 portal-3

Los cigarrillos electrónicos provocan inflamación en el intestino

We already hosted many doubts about electronic cigarettes, to which we now add the conclusions of a new study: which can cause inflammation in the intestine.

In the study Has been published this January 5, 2021 in the magazine iScience. This is the first study to demonstrate how chronic exposure to e-cigarettes increases the gut's susceptibility to bacterial infections.

Intestinal barrier alteration

The results of the study suggest that the chemical components of electronic cigarettes, specifically propylene glycol and vegetable glycerol, they disrupt the intestinal barrier and trigger inflammation in the body, which can lead to a variety of health problems.

Everything we eat or drink, our lifestyle choices in other words, has the ability to affect our gut microbes, gut barrier, and overall health. We now know that what we smoke, like e-cigarettes, also negatively impacts it.

For the study, the team used three-dimensional models of human intestinal tracts generated from patient cells and simulated what happens when vapors from e-cigarettes enter the intestinal lining. The researchers validated the findings using mouse models.

Diferentes Modelos De Ecigs

To produce the three-dimensional intestinal organoids, the researchers collected stem cells from patients' biopsies during colonoscopies and They grew them in vitro. The stem cells differentiated into four different types of cells that make up the intestinal lining. Finally, the team exposed the organoids to the liquid vapor of the e-cigarette, mimicking the frequency of a chronic vaper.

'Given the importance of the intestinal barrier in maintaining the body's immune homeostasis, the findings provide valuable information about the Possible long-term harmful effects of chronic use of electronic cigarettes on our health.


The news

Electronic cigarettes cause inflammation in the intestine

was originally published in

Xataka Science

by
Sergio Parra

.